Modulation of Immune Responses in Murine Pulmonary Histoplasmosis
نویسندگان
چکیده
منابع مشابه
Pulmonary histoplasmosis.
Pulmonary manifestations of histoplasmosis were last reviewed in Seminars in 2004. This review highlights the management of the most common clinical syndromes, emphasizing recognition, diagnosis, and treatment. The reader is referred to the earlier review for subjects not fully addressed herein. Knowledge of the utility of serological testing is essential, particularly when antigen tests and cu...
متن کاملPulmonary histoplasmosis.
Human infection by the fungus Histoplasma capsulatum produces two syndromes which are similar to those following infection by Coccid&oides immitis. The first syndrome to be recognized was a generalized affection of the reticuloendothelial system, described by Darling (1906, 1908, and 1909) and fully detailed by DeMonbreun (1934). The second syndrome is characterized by pulmonary calcification a...
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Sordarins are new antifungals which inhibit fungal protein synthesis by blocking elongation factor 2. Three compounds were evaluated in a murine model of histoplasmosis. Immune-competent mice were infected intravenously with 10(6) to 10(8) CFU of Histoplasma capsulatum yeast cells. Mice were treated either orally with sordarins or fluconazole from day 2 through 8 after infection or intraperiton...
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Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma capsulatum, which can be isolated from soil contaminated with droppings from birds or bats. Chronic cavitary pulmonary histoplasmosis is one of the rarest clinical presentations of this disease. The differential diagnosis with tuberculosis should be made in patients presenting with cavitated lesions in upp...
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Echinacea preparations are widely used herbal medicines for the prevention and treatment of colds and minor infections. There is little evidence for the individual components in Echinacea that contribute to immune regulatory activity. Activity of an ethanolic Echinacea extract and several constituents, including cichoric acid, have been examined using three in vitro measures of macrophage immun...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 1997
ISSN: 0022-1899,1537-6613
DOI: 10.1086/513989